BDBM50106548 CHEMBL440164::{6-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-but-1-enyl)-cyclopentyl]-hex-4-enyl}-methyl-phosphinic acid

SMILES: CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1

InChI Key: InChIKey=RXTAVSNCEWWPED-BXZMMUGYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50106548   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50106548 (CHEMBL440164 | {6-[3,5-Dihydroxy-2-(3-hydroxy-4-ph...) Show SMILES CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1 |w:7.6| Show InChI InChI=1S/C22H33O6P/c1-29(26,27)14-8-3-2-7-11-19-20(22(25)15-21(19)24)13-12-17(23)16-28-18-9-5-4-6-10-18/h2,4-7,9-10,12-13,17,19-25H,3,8,11,14-16H2,1H3,(H,26,27)/b7-2?,13-12+/t17-,19-,20-,21+,22-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding of the compound at prostanoid IP receptor using [3H]-Iloprost as radioligand				J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50106548 (CHEMBL440164 | {6-[3,5-Dihydroxy-2-(3-hydroxy-4-ph...) Show SMILES CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1 |w:7.6| Show InChI InChI=1S/C22H33O6P/c1-29(26,27)14-8-3-2-7-11-19-20(22(25)15-21(19)24)13-12-17(23)16-28-18-9-5-4-6-10-18/h2,4-7,9-10,12-13,17,19-25H,3,8,11,14-16H2,1H3,(H,26,27)/b7-2?,13-12+/t17-,19-,20-,21+,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding of the compound at EP2 human prostaglandin receptor				J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50106548 (CHEMBL440164 | {6-[3,5-Dihydroxy-2-(3-hydroxy-4-ph...) Show SMILES CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1 |w:7.6| Show InChI InChI=1S/C22H33O6P/c1-29(26,27)14-8-3-2-7-11-19-20(22(25)15-21(19)24)13-12-17(23)16-28-18-9-5-4-6-10-18/h2,4-7,9-10,12-13,17,19-25H,3,8,11,14-16H2,1H3,(H,26,27)/b7-2?,13-12+/t17-,19-,20-,21+,22-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding of the compound at DP human prostaglandin receptor using [3H]- PGD-2 as radioligand				J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50106548 (CHEMBL440164 | {6-[3,5-Dihydroxy-2-(3-hydroxy-4-ph...) Show SMILES CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1 |w:7.6| Show InChI InChI=1S/C22H33O6P/c1-29(26,27)14-8-3-2-7-11-19-20(22(25)15-21(19)24)13-12-17(23)16-28-18-9-5-4-6-10-18/h2,4-7,9-10,12-13,17,19-25H,3,8,11,14-16H2,1H3,(H,26,27)/b7-2?,13-12+/t17-,19-,20-,21+,22-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding of the compound at FP human prostaglandin receptor using [3H]-PGF-2 alpha as radioligand				J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50106548 (CHEMBL440164 | {6-[3,5-Dihydroxy-2-(3-hydroxy-4-ph...) Show SMILES CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1 |w:7.6| Show InChI InChI=1S/C22H33O6P/c1-29(26,27)14-8-3-2-7-11-19-20(22(25)15-21(19)24)13-12-17(23)16-28-18-9-5-4-6-10-18/h2,4-7,9-10,12-13,17,19-25H,3,8,11,14-16H2,1H3,(H,26,27)/b7-2?,13-12+/t17-,19-,20-,21+,22-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding of the compound at EP1 human prostaglandin receptor using [3H]-PGE-2 as radioligand				J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50106548 (CHEMBL440164 | {6-[3,5-Dihydroxy-2-(3-hydroxy-4-ph...) Show SMILES CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1 |w:7.6| Show InChI InChI=1S/C22H33O6P/c1-29(26,27)14-8-3-2-7-11-19-20(22(25)15-21(19)24)13-12-17(23)16-28-18-9-5-4-6-10-18/h2,4-7,9-10,12-13,17,19-25H,3,8,11,14-16H2,1H3,(H,26,27)/b7-2?,13-12+/t17-,19-,20-,21+,22-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding of the compound at TP human prostaglandin receptor using [3H]-SQ-29,548 as radioligand				J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50106548 (CHEMBL440164 | {6-[3,5-Dihydroxy-2-(3-hydroxy-4-ph...) Show SMILES CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1 |w:7.6| Show InChI InChI=1S/C22H33O6P/c1-29(26,27)14-8-3-2-7-11-19-20(22(25)15-21(19)24)13-12-17(23)16-28-18-9-5-4-6-10-18/h2,4-7,9-10,12-13,17,19-25H,3,8,11,14-16H2,1H3,(H,26,27)/b7-2?,13-12+/t17-,19-,20-,21+,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding of the compound at EP4 human prostaglandin receptor using [3H]-PGE-2 as radioligand				J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50106548 (CHEMBL440164 | {6-[3,5-Dihydroxy-2-(3-hydroxy-4-ph...) Show SMILES CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1 |w:7.6| Show InChI InChI=1S/C22H33O6P/c1-29(26,27)14-8-3-2-7-11-19-20(22(25)15-21(19)24)13-12-17(23)16-28-18-9-5-4-6-10-18/h2,4-7,9-10,12-13,17,19-25H,3,8,11,14-16H2,1H3,(H,26,27)/b7-2?,13-12+/t17-,19-,20-,21+,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding of the compound at EP3 human prostaglandin receptor using [3H]-PGE-2 as radioligand				J Med Chem 44: 4157-69 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NNP
					More data for this Ligand-Target Pair