BDBM50106597 CHEMBL133983::[1-(2-Benzyl-1-oxo-3-thioxo-octahydro-4a(S)-pyrido[1,2-c]pyrimidin-5(R)-ylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester
SMILES: CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N[C@@H]1CCCN2[C@H]1CC(=S)N(Cc1ccccc1)C2=O
InChI Key: InChIKey=OVFVVPNJKQOVDQ-ITNFAHLUSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CCKBR (RAT) | BDBM50106597 (CHEMBL133983 | [1-(2-Benzyl-1-oxo-3-thioxo-octahyd...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL | Assay Description Inhibition of [3H]pCCK-8 binding to cholecystokinin type B receptor of rat cerebral cortex | J Med Chem 44: 4196-206 (2001) BindingDB Entry DOI: 10.7270/Q2TD9Z23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (RAT) | BDBM50106597 (CHEMBL133983 | [1-(2-Benzyl-1-oxo-3-thioxo-octahyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.83 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL | Assay Description Inhibition of [3H]pCCK-8 binding to cholecystokinin type A receptor of rat pancreas | J Med Chem 44: 4196-206 (2001) BindingDB Entry DOI: 10.7270/Q2TD9Z23 | |||||||||||
More data for this Ligand-Target Pair |