BDBM50106835 CHEMBL317920::N-(2-Hydroxy-5-{(R)-1-hydroxy-2-[(R)-1-(4-methoxy-naphthalen-1-yl)-2-phenyl-ethylamino]-ethyl}-phenyl)-methanesulfonamide
SMILES: COc1ccc([C@@H](Cc2ccccc2)NC[C@H](O)c2ccc(O)c(NS(C)(=O)=O)c2)c2ccccc12
InChI Key: InChIKey=GKVZJTQXVQMYBY-SQHAQQRYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-3 adrenergic receptor (Homo sapiens (Human)) | BDBM50106835 (CHEMBL317920 | N-(2-Hydroxy-5-{(R)-1-hydroxy-2-[(R...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity to CHO cells expressing the cloned human beta-3 adrenergic receptor in the presence of [125I]-iodocyanopindolol | Bioorg Med Chem Lett 11: 3041-4 (2001) BindingDB Entry DOI: 10.7270/Q2794402 | |||||||||||
More data for this Ligand-Target Pair |