BDBM50106974 4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenylamino)-piperidine-1-carboxylic acid methylamide::CHEMBL107012

SMILES: CNC(=O)N1CCC(CC1)Nc1ccc(CCNC[C@H](O)COc2ccc(O)cc2)cc1

InChI Key: InChIKey=OTFOLBPJZMDYME-QFIPXVFZSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50106974 (4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propy...) Show SMILES CNC(=O)N1CCC(CC1)Nc1ccc(CCNC[C@H](O)COc2ccc(O)cc2)cc1 Show InChI InChI=1S/C24H34N4O4/c1-25-24(31)28-14-11-20(12-15-28)27-19-4-2-18(3-5-19)10-13-26-16-22(30)17-32-23-8-6-21(29)7-9-23/h2-9,20,22,26-27,29-30H,10-17H2,1H3,(H,25,31)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro agonistic activity assessed by measurement of cAMP accumulation level in CHO cells expressing human beta1-AR receptor				Bioorg Med Chem Lett 11: 3123-7 (2001) BindingDB Entry DOI: 10.7270/Q26D5S92
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50106974 (4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propy...) Show SMILES CNC(=O)N1CCC(CC1)Nc1ccc(CCNC[C@H](O)COc2ccc(O)cc2)cc1 Show InChI InChI=1S/C24H34N4O4/c1-25-24(31)28-14-11-20(12-15-28)27-19-4-2-18(3-5-19)10-13-26-16-22(30)17-32-23-8-6-21(29)7-9-23/h2-9,20,22,26-27,29-30H,10-17H2,1H3,(H,25,31)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro agonistic activity assessed by measurement of cAMP accumulation level in CHO cells expressing human beta3-AR receptor				Bioorg Med Chem Lett 11: 3123-7 (2001) BindingDB Entry DOI: 10.7270/Q26D5S92
					More data for this Ligand-Target Pair