BDBM50106997 1-((3S,4S)-1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-(3-phenyl-propyl)-piperidine::CHEMBL321267

SMILES: C(CC1CCN(C[C@H]2CN(CC3CCCCC3)C[C@@H]2c2ccccc2)CC1)Cc1ccccc1

InChI Key: InChIKey=JWSRHFLPBLYQPA-AJQTZOPKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50106997 (1-((3S,4S)-1-Cyclohexylmethyl-4-phenyl-pyrrolidin-...) Show SMILES C(CC1CCN(C[C@H]2CN(CC3CCCCC3)C[C@@H]2c2ccccc2)CC1)Cc1ccccc1 Show InChI InChI=1S/C32H46N2/c1-4-11-27(12-5-1)15-10-16-28-19-21-33(22-20-28)24-31-25-34(23-29-13-6-2-7-14-29)26-32(31)30-17-8-3-9-18-30/h1,3-5,8-9,11-12,17-18,28-29,31-32H,2,6-7,10,13-16,19-26H2/t31-,32+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranes				Bioorg Med Chem Lett 11: 3137-41 (2001) BindingDB Entry DOI: 10.7270/Q2XW4J4W
					More data for this Ligand-Target Pair