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BDBM50107022 CHEMBL110409::N-[1-Amino-1-(7-trifluoromethyl-3,4-dihydro-2H-quinolin-1-yl)-meth-(E)-ylidene]-4-methyl-benzamide

SMILES: Cc1ccc(cc1)C(=O)NC(=N)N1CCCc2ccc(cc12)C(F)(F)F

InChI Key: InChIKey=XJTOLIYGPQFIEG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107022   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 2 alpha subunit


(Homo sapiens (Human))		BDBM50107022
PNG
(CHEMBL110409 | N-[1-Amino-1-(7-trifluoromethyl-3,4...)
Show SMILES Cc1ccc(cc1)C(=O)NC(=N)N1CCCc2ccc(cc12)C(F)(F)F
Show InChI InChI=1S/C19H18F3N3O/c1-12-4-6-14(7-5-12)17(26)24-18(23)25-10-2-3-13-8-9-15(11-16(13)25)19(20,21)22/h4-9,11H,2-3,10H2,1H3,(H2,23,24,26)
PDB

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PC sid
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PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel

Bioorg Med Chem Lett 11: 3151-5 (2001)


BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair