BDBM50107051 CHEMBL108627::N-(4-Methyl-benzoyl)-N'-naphthalen-1-ylmethyl-guanidine

SMILES: Cc1ccc(cc1)C(=O)NC(N)=NCc1cccc2ccccc12

InChI Key: InChIKey=VPWXWSXUPGZSLH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50107051 (CHEMBL108627 | N-(4-Methyl-benzoyl)-N'-naphthalen-...) Show SMILES Cc1ccc(cc1)C(=O)NC(N)=NCc1cccc2ccccc12 |w:12.13| Show InChI InChI=1S/C20H19N3O/c1-14-9-11-16(12-10-14)19(24)23-20(21)22-13-17-7-4-6-15-5-2-3-8-18(15)17/h2-12H,13H2,1H3,(H3,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 alpha subunit (Homo sapiens (Human))	BDBM50107051 (CHEMBL108627 | N-(4-Methyl-benzoyl)-N'-naphthalen-...) Show SMILES Cc1ccc(cc1)C(=O)NC(N)=NCc1cccc2ccccc12 |w:12.13| Show InChI InChI=1S/C20H19N3O/c1-14-9-11-16(12-10-14)19(24)23-20(21)22-13-17-7-4-6-15-5-2-3-8-18(15)17/h2-12H,13H2,1H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair