BDBM50107145 CHEMBL135144::[2-(Carboxymethyl-hydrazono)-3-(4-chloro-benzyl)-2,3-dihydro-benzoimidazol-1-yl]-oxo-acetic acid

SMILES: OC(=O)CN\N=c1/n(Cc2ccc(Cl)cc2)c2ccccc2n1C(=O)C(O)=O

InChI Key: InChIKey=GIUHZKVBALEXFS-DYTRJAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (Rattus norvegicus)	BDBM50107145 (CHEMBL135144 | [2-(Carboxymethyl-hydrazono)-3-(4-c...) Show SMILES OC(=O)CN\N=c1/n(Cc2ccc(Cl)cc2)c2ccccc2n1C(=O)C(O)=O Show InChI InChI=1S/C18H15ClN4O5/c19-12-7-5-11(6-8-12)10-22-13-3-1-2-4-14(13)23(16(26)17(27)28)18(22)21-20-9-15(24)25/h1-8,20H,9-10H2,(H,24,25)(H,27,28)/b21-18+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lens				J Med Chem 44: 4359-69 (2001) BindingDB Entry DOI: 10.7270/Q21N80FB
					More data for this Ligand-Target Pair