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SMILES: OC(=O)Cc1nnc2n(Cc3ccccc3)c3ccccc3n2c1=O

InChI Key: InChIKey=GXYLQKGHRLRVOB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107146   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1


(Rattus norvegicus)		BDBM50107146
PNG
((10-Benzyl-4-oxo-4,10-dihydro-benzo[4,5]imidazo[2,...)
Show SMILES OC(=O)Cc1nnc2n(Cc3ccccc3)c3ccccc3n2c1=O
Show InChI InChI=1S/C18H14N4O3/c23-16(24)10-13-17(25)22-15-9-5-4-8-14(15)21(18(22)20-19-13)11-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,23,24)
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PubMed
n/an/a 5.44E+3n/an/an/an/an/an/a



Università di Pisa

Curated by ChEMBL


Assay Description
Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lens

J Med Chem 44: 4359-69 (2001)


BindingDB Entry DOI: 10.7270/Q21N80FB
More data for this
Ligand-Target Pair