BDBM50107158 CHEMBL136452::[3-Benzyl-2-(carboxymethyl-hydrazono)-2,3-dihydro-benzoimidazol-1-yl]-oxo-acetic acid

SMILES: OC(=O)CN\N=c1/n(Cc2ccccc2)c2ccccc2n1C(=O)C(O)=O

InChI Key: InChIKey=UOVICTJGHCTYEC-CZIZESTLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (Rattus norvegicus)	BDBM50107158 (CHEMBL136452 | [3-Benzyl-2-(carboxymethyl-hydrazon...) Show SMILES OC(=O)CN\N=c1/n(Cc2ccccc2)c2ccccc2n1C(=O)C(O)=O Show InChI InChI=1S/C18H16N4O5/c23-15(24)10-19-20-18-21(11-12-6-2-1-3-7-12)13-8-4-5-9-14(13)22(18)16(25)17(26)27/h1-9,19H,10-11H2,(H,23,24)(H,26,27)/b20-18+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibitory concentration to aldose reductase (ALR-2) obtained from rat lens				J Med Chem 44: 4359-69 (2001) BindingDB Entry DOI: 10.7270/Q21N80FB
					More data for this Ligand-Target Pair