BDBM50107296 (E)-1-(2,4-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one::1-(2,4-Dimethoxy-phenyl)-3-naphthalen-1-yl-propenone::1-(2,4-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one::CHEMBL139856::WR-289016

SMILES: COc1ccc(C(=O)\C=C\c2cccc3ccccc23)c(OC)c1

InChI Key: InChIKey=MLJPSPKBQRTVGK-JLHYYAGUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase Pfmrk (Plasmodium falciparum)	BDBM50107296 ((E)-1-(2,4-dimethoxyphenyl)-3-(naphthalen-1-yl)pro...) Show SMILES COc1ccc(C(=O)\C=C\c2cccc3ccccc23)c(OC)c1 Show InChI InChI=1S/C21H18O3/c1-23-17-11-12-19(21(14-17)24-2)20(22)13-10-16-8-5-7-15-6-3-4-9-18(15)16/h3-14H,1-2H3/b13-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation counting				Bioorg Med Chem Lett 19: 1982-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.042 BindingDB Entry DOI: 10.7270/Q2P26Z1T
					More data for this Ligand-Target Pair