BDBM50107495 CHEMBL153415::N-Biphenyl-2-ylmethyl-2-[2-(4-fluoro-benzylsulfanyl)-4-oxo-5-pyrimidin-5-ylmethyl-4H-pyrimidin-1-yl]-acetamide

SMILES: Fc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2CC(=O)NCc2ccccc2-c2ccccc2)cc1

InChI Key: InChIKey=AQLJRZFGNYRECL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50107495 (CHEMBL153415 | N-Biphenyl-2-ylmethyl-2-[2-(4-fluor...) Show SMILES Fc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2CC(=O)NCc2ccccc2-c2ccccc2)cc1 Show InChI InChI=1S/C31H26FN5O2S/c32-27-12-10-22(11-13-27)20-40-31-36-30(39)26(14-23-15-33-21-34-16-23)18-37(31)19-29(38)35-17-25-8-4-5-9-28(25)24-6-2-1-3-7-24/h1-13,15-16,18,21H,14,17,19-20H2,(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	194	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Lp-PLA2 (Lp-PLA2).				Bioorg Med Chem Lett 12: 51-5 (2001) BindingDB Entry DOI: 10.7270/Q2862FR5
					More data for this Ligand-Target Pair