BDBM50107572 (R)-N*4*-Hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-yl)-2-(2'-methyl-biphenyl-4-ylmethyl)-succinamide::CHEMBL266245

SMILES: Cc1ccccc1-c1ccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1

InChI Key: InChIKey=BDVACXGBIHLFIX-QQSVUBKYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50107572 ((R)-N*4*-Hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-y...) Show SMILES Cc1ccccc1-c1ccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1 Show InChI InChI=1S/C27H28N2O4/c1-17-6-2-4-8-22(17)19-12-10-18(11-13-19)14-21(16-25(31)29-33)27(32)28-26-23-9-5-3-7-20(23)15-24(26)30/h2-13,21,24,26,30,33H,14-16H2,1H3,(H,28,32)(H,29,31)/t21-,24-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for human gelatinase A (MMP-2)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50107572 ((R)-N*4*-Hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-y...) Show SMILES Cc1ccccc1-c1ccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1 Show InChI InChI=1S/C27H28N2O4/c1-17-6-2-4-8-22(17)19-12-10-18(11-13-19)14-21(16-25(31)29-33)27(32)28-26-23-9-5-3-7-20(23)15-24(26)30/h2-13,21,24,26,30,33H,14-16H2,1H3,(H,28,32)(H,29,31)/t21-,24-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for human gelatinase B (MMP-9)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50107572 ((R)-N*4*-Hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-y...) Show SMILES Cc1ccccc1-c1ccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1 Show InChI InChI=1S/C27H28N2O4/c1-17-6-2-4-8-22(17)19-12-10-18(11-13-19)14-21(16-25(31)29-33)27(32)28-26-23-9-5-3-7-20(23)15-24(26)30/h2-13,21,24,26,30,33H,14-16H2,1H3,(H,28,32)(H,29,31)/t21-,24-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for neutrophil collagenase (MMP-1)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair