BDBM50107580 (R)-N*4*-Hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-yl)-2-(3'-isopropyl-biphenyl-4-ylmethyl)-succinamide::CHEMBL268381

SMILES: CC(C)c1cccc(c1)-c1ccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1

InChI Key: InChIKey=TVIRTWMMZYUJOB-INOCPDNRSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50107580 ((R)-N*4*-Hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-y...) Show SMILES CC(C)c1cccc(c1)-c1ccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1 Show InChI InChI=1S/C29H32N2O4/c1-18(2)21-7-5-8-22(15-21)20-12-10-19(11-13-20)14-24(17-27(33)31-35)29(34)30-28-25-9-4-3-6-23(25)16-26(28)32/h3-13,15,18,24,26,28,32,35H,14,16-17H2,1-2H3,(H,30,34)(H,31,33)/t24-,26-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for human gelatinase A (MMP-2)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50107580 ((R)-N*4*-Hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-y...) Show SMILES CC(C)c1cccc(c1)-c1ccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1 Show InChI InChI=1S/C29H32N2O4/c1-18(2)21-7-5-8-22(15-21)20-12-10-19(11-13-20)14-24(17-27(33)31-35)29(34)30-28-25-9-4-3-6-23(25)16-26(28)32/h3-13,15,18,24,26,28,32,35H,14,16-17H2,1-2H3,(H,30,34)(H,31,33)/t24-,26-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for human gelatinase B (MMP-9)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50107580 ((R)-N*4*-Hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-y...) Show SMILES CC(C)c1cccc(c1)-c1ccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1 Show InChI InChI=1S/C29H32N2O4/c1-18(2)21-7-5-8-22(15-21)20-12-10-19(11-13-20)14-24(17-27(33)31-35)29(34)30-28-25-9-4-3-6-23(25)16-26(28)32/h3-13,15,18,24,26,28,32,35H,14,16-17H2,1-2H3,(H,30,34)(H,31,33)/t24-,26-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for neutrophil collagenase (MMP-1)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair