BDBM50107583 (R)-2-(3'-Fluoro-biphenyl-4-ylmethyl)-N*4*-hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-yl)-succinamide::CHEMBL8496

SMILES: ONC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(F)c1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key: InChIKey=KLPLOGXKUWGLSE-XRODADMRSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50107583 ((R)-2-(3'-Fluoro-biphenyl-4-ylmethyl)-N*4*-hydroxy...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(F)c1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C26H25FN2O4/c27-21-6-3-5-18(13-21)17-10-8-16(9-11-17)12-20(15-24(31)29-33)26(32)28-25-22-7-2-1-4-19(22)14-23(25)30/h1-11,13,20,23,25,30,33H,12,14-15H2,(H,28,32)(H,29,31)/t20-,23-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for human gelatinase B (MMP-9)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50107583 ((R)-2-(3'-Fluoro-biphenyl-4-ylmethyl)-N*4*-hydroxy...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(F)c1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C26H25FN2O4/c27-21-6-3-5-18(13-21)17-10-8-16(9-11-17)12-20(15-24(31)29-33)26(32)28-25-22-7-2-1-4-19(22)14-23(25)30/h1-11,13,20,23,25,30,33H,12,14-15H2,(H,28,32)(H,29,31)/t20-,23-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for human gelatinase A (MMP-2)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50107583 ((R)-2-(3'-Fluoro-biphenyl-4-ylmethyl)-N*4*-hydroxy...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(F)c1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C26H25FN2O4/c27-21-6-3-5-18(13-21)17-10-8-16(9-11-17)12-20(15-24(31)29-33)26(32)28-25-22-7-2-1-4-19(22)14-23(25)30/h1-11,13,20,23,25,30,33H,12,14-15H2,(H,28,32)(H,29,31)/t20-,23-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Company Curated by ChEMBL					Assay Description Binding affinity for neutrophil collagenase (MMP-1)				Bioorg Med Chem Lett 12: 101-4 (2001) BindingDB Entry DOI: 10.7270/Q2R49Q1C
					More data for this Ligand-Target Pair