BDBM50107691 (2,4-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-methanone::CHEMBL142075

SMILES: COc1ccc(C(=O)c2cc3cc(OC)ccc3[nH]2)c(OC)c1

InChI Key: InChIKey=FTXHWHLVBLAUSD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin (Bos taurus)	BDBM50107691 ((2,4-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-m...) Show SMILES COc1ccc(C(=O)c2cc3cc(OC)ccc3[nH]2)c(OC)c1 Show InChI InChI=1S/C18H17NO4/c1-21-12-5-7-15-11(8-12)9-16(19-15)18(20)14-6-4-13(22-2)10-17(14)23-3/h4-10,19H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.				J Med Chem 44: 4535-53 (2001) BindingDB Entry DOI: 10.7270/Q2BZ65CN
					More data for this Ligand-Target Pair