BDBM50107717 1,3-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl)-1,2,5-thiadiazol-3-ylsulfanyl]propane::CHEMBL337131

SMILES: CN1CCC=C(C1)c1nsnc1SCCCSc1nsnc1C1=CCCN(C)C1

InChI Key: InChIKey=TWGGDUAUQDVEQJ-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50107717 (1,3-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl)...) Show SMILES CN1CCC=C(C1)c1nsnc1SCCCSc1nsnc1C1=CCCN(C)C1 |c:4,t:25| Show InChI InChI=1S/C19H26N6S4/c1-24-8-3-6-14(12-24)16-18(22-28-20-16)26-10-5-11-27-19-17(21-29-23-19)15-7-4-9-25(2)13-15/h6-7H,3-5,8-13H2,1-2H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Binding affinity towards M1 muscarinic receptor expressed in A9 L cells by diaplacing [3H]-(R)-QNB radioligand.				J Med Chem 44: 4563-76 (2001) BindingDB Entry DOI: 10.7270/Q2765DN7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50107717 (1,3-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl)...) Show SMILES CN1CCC=C(C1)c1nsnc1SCCCSc1nsnc1C1=CCCN(C)C1 |c:4,t:25| Show InChI InChI=1S/C19H26N6S4/c1-24-8-3-6-14(12-24)16-18(22-28-20-16)26-10-5-11-27-19-17(21-29-23-19)15-7-4-9-25(2)13-15/h6-7H,3-5,8-13H2,1-2H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Agonistic activity against M1 muscarinic receptor expressed in A9 L cells.				J Med Chem 44: 4563-76 (2001) BindingDB Entry DOI: 10.7270/Q2765DN7
					More data for this Ligand-Target Pair