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SMILES: CC1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=UWQLUXHEVKAZSK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50107747 (CHEMBL3600830) Show SMILES CC1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H27ClN2O/c1-21-14-16-30(17-15-21)18-19-31-27-12-3-22(4-13-27)2-10-26-11-7-24(20-29-26)23-5-8-25(28)9-6-23/h3-9,11-13,20-21H,14-19H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of muscarinic M1 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107747 (CHEMBL3600830) Show SMILES CC1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H27ClN2O/c1-21-14-16-30(17-15-21)18-19-31-27-12-3-22(4-13-27)2-10-26-11-7-24(20-29-26)23-5-8-25(28)9-6-23/h3-9,11-13,20-21H,14-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50107747 (CHEMBL3600830) Show SMILES CC1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H27ClN2O/c1-21-14-16-30(17-15-21)18-19-31-27-12-3-22(4-13-27)2-10-26-11-7-24(20-29-26)23-5-8-25(28)9-6-23/h3-9,11-13,20-21H,14-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of CYP2D6 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50107747 (CHEMBL3600830) Show SMILES CC1CCN(CCOc2ccc(cc2)C#Cc2ccc(cn2)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H27ClN2O/c1-21-14-16-30(17-15-21)18-19-31-27-12-3-22(4-13-27)2-10-26-11-7-24(20-29-26)23-5-8-25(28)9-6-23/h3-9,11-13,20-21H,14-19H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of 5HT2A receptor (unknown origin)				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair