null

SMILES: OC[C@H]1CCCN1CCOc1ccc(cc1)C#Cc1ccc(cn1)-c1ccc(Cl)cc1

InChI Key: InChIKey=GGTZHCUZWHTXIC-RUZDIDTESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50107750 (CHEMBL3601022) Show SMILES OC[C@H]1CCCN1CCOc1ccc(cc1)C#Cc1ccc(cn1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H25ClN2O2/c27-23-9-6-21(7-10-23)22-8-12-24(28-18-22)11-3-20-4-13-26(14-5-20)31-17-16-29-15-1-2-25(29)19-30/h4-10,12-14,18,25,30H,1-2,15-17,19H2/t25-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of muscarinic M1 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107750 (CHEMBL3601022) Show SMILES OC[C@H]1CCCN1CCOc1ccc(cc1)C#Cc1ccc(cn1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H25ClN2O2/c27-23-9-6-21(7-10-23)22-8-12-24(28-18-22)11-3-20-4-13-26(14-5-20)31-17-16-29-15-1-2-25(29)19-30/h4-10,12-14,18,25,30H,1-2,15-17,19H2/t25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50107750 (CHEMBL3601022) Show SMILES OC[C@H]1CCCN1CCOc1ccc(cc1)C#Cc1ccc(cn1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H25ClN2O2/c27-23-9-6-21(7-10-23)22-8-12-24(28-18-22)11-3-20-4-13-26(14-5-20)31-17-16-29-15-1-2-25(29)19-30/h4-10,12-14,18,25,30H,1-2,15-17,19H2/t25-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of CYP2D6 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50107750 (CHEMBL3601022) Show SMILES OC[C@H]1CCCN1CCOc1ccc(cc1)C#Cc1ccc(cn1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H25ClN2O2/c27-23-9-6-21(7-10-23)22-8-12-24(28-18-22)11-3-20-4-13-26(14-5-20)31-17-16-29-15-1-2-25(29)19-30/h4-10,12-14,18,25,30H,1-2,15-17,19H2/t25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of 5HT2A receptor (unknown origin)				Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair