null
SMILES: Cc1cc(ccc1OCCN1CCC[C@H]1CO)C#Cc1ccc(cn1)-c1ccc(Cl)cc1
InChI Key: InChIKey=ZOKQZJZIENINDP-SANMLTNESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50107751 (CHEMBL3601023) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 665 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL | Assay Description Inhibition of muscarinic M1 receptor (unknown origin) | Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50107751 (CHEMBL3601023) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method | Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50107751 (CHEMBL3601023) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL | Assay Description Inhibition of CYP2D6 receptor (unknown origin) | Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50107751 (CHEMBL3601023) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL | Assay Description Inhibition of 5HT2A receptor (unknown origin) | Bioorg Med Chem Lett 25: 3264-9 (2015) BindingDB Entry DOI: 10.7270/Q25D8TMB | |||||||||||
More data for this Ligand-Target Pair |