BDBM50107778 Biphenyl-2-carboxylic acid (2-benzenesulfonylamino-indan-5-yl)-amide::CHEMBL143535

SMILES: O=C(Nc1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1)c1ccccc1-c1ccccc1

InChI Key: InChIKey=PYHWTMOCTYEEAJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein (Homo sapiens (Human))	BDBM50107778 (Biphenyl-2-carboxylic acid (2-benzenesulfonylamino...) Show SMILES O=C(Nc1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C28H24N2O3S/c31-28(27-14-8-7-13-26(27)20-9-3-1-4-10-20)29-23-16-15-21-17-24(19-22(21)18-23)30-34(32,33)25-11-5-2-6-12-25/h1-16,18,24,30H,17,19H2,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description In vitro inhibitory activity against MTP using MTP transfer assay				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair
Apolipoprotein B-100 (Homo sapiens (Human))	BDBM50107778 (Biphenyl-2-carboxylic acid (2-benzenesulfonylamino...) Show SMILES O=C(Nc1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C28H24N2O3S/c31-28(27-14-8-7-13-26(27)20-9-3-1-4-10-20)29-23-16-15-21-17-24(19-22(21)18-23)30-34(32,33)25-11-5-2-6-12-25/h1-16,18,24,30H,17,19H2,(H,29,31)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nM				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair