BDBM50108305 1,2,3,4-Tetrahydro-benzo[4,5]imidazo[1,2-a]pyrazine::CHEMBL6503

SMILES: C1Cn2c(CN1)nc1ccccc21

InChI Key: InChIKey=CVGPZQMGLKRVJV-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50108305 (1,2,3,4-Tetrahydro-benzo[4,5]imidazo[1,2-a]pyrazin...) Show SMILES C1Cn2c(CN1)nc1ccccc21 Show InChI InChI=1S/C10H11N3/c1-2-4-9-8(3-1)12-10-7-11-5-6-13(9)10/h1-4,11H,5-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from human 5-hydroxytryptamine 2A receptor				Bioorg Med Chem Lett 12: 155-8 (2001) BindingDB Entry DOI: 10.7270/Q21G0KKD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50108305 (1,2,3,4-Tetrahydro-benzo[4,5]imidazo[1,2-a]pyrazin...) Show SMILES C1Cn2c(CN1)nc1ccccc21 Show InChI InChI=1S/C10H11N3/c1-2-4-9-8(3-1)12-10-7-11-5-6-13(9)10/h1-4,11H,5-7H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2C receptor.				Bioorg Med Chem Lett 12: 155-8 (2001) BindingDB Entry DOI: 10.7270/Q21G0KKD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50108305 (1,2,3,4-Tetrahydro-benzo[4,5]imidazo[1,2-a]pyrazin...) Show SMILES C1Cn2c(CN1)nc1ccccc21 Show InChI InChI=1S/C10H11N3/c1-2-4-9-8(3-1)12-10-7-11-5-6-13(9)10/h1-4,11H,5-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from human 5-hydroxytryptamine 2A receptor				Bioorg Med Chem Lett 12: 155-8 (2001) BindingDB Entry DOI: 10.7270/Q21G0KKD
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50108305 (1,2,3,4-Tetrahydro-benzo[4,5]imidazo[1,2-a]pyrazin...) Show SMILES C1Cn2c(CN1)nc1ccccc21 Show InChI InChI=1S/C10H11N3/c1-2-4-9-8(3-1)12-10-7-11-5-6-13(9)10/h1-4,11H,5-7H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of [3H]RX-821002 from alpha-2 adrenergic receptor				Bioorg Med Chem Lett 14: 1003-5 (2004) Article DOI: 10.1016/j.bmcl.2003.12.033 BindingDB Entry DOI: 10.7270/Q2NK3DGR
					More data for this Ligand-Target Pair