BDBM50108433 3-(4-Chloro-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one::CHEMBL60030

SMILES: Clc1ccc(cc1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O

InChI Key: InChIKey=XTHNRGZLGVFIMJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50108433 (3-(4-Chloro-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-...) Show SMILES Clc1ccc(cc1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O Show InChI InChI=1S/C23H23ClN2O/c24-20-12-10-18(11-13-20)21-9-6-16-26(23(21)27)22(17-25-14-4-5-15-25)19-7-2-1-3-8-19/h1-3,6-13,16,22H,4-5,14-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Binding affinity towards delta opioid receptor by the displacement of [125I]-Deltorphin				Bioorg Med Chem Lett 12: 197-200 (2001) BindingDB Entry DOI: 10.7270/Q28051XH
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50108433 (3-(4-Chloro-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-...) Show SMILES Clc1ccc(cc1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O Show InChI InChI=1S/C23H23ClN2O/c24-20-12-10-18(11-13-20)21-9-6-16-26(23(21)27)22(17-25-14-4-5-15-25)19-7-2-1-3-8-19/h1-3,6-13,16,22H,4-5,14-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin A				Bioorg Med Chem Lett 12: 197-200 (2001) BindingDB Entry DOI: 10.7270/Q28051XH
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50108433 (3-(4-Chloro-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-...) Show SMILES Clc1ccc(cc1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O Show InChI InChI=1S/C23H23ClN2O/c24-20-12-10-18(11-13-20)21-9-6-16-26(23(21)27)22(17-25-14-4-5-15-25)19-7-2-1-3-8-19/h1-3,6-13,16,22H,4-5,14-15,17H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Binding affinity towards mu opioid receptor by the displacement of [125I]-Enkephalin				Bioorg Med Chem Lett 12: 197-200 (2001) BindingDB Entry DOI: 10.7270/Q28051XH
					More data for this Ligand-Target Pair