BDBM50108494 2-Methyl-furan-3-carboxylic acid (4-{[2-(6-[1,4']bipiperidinyl-1'-yl-6-oxo-hexyloxy)-4-methyl-phenyl]-methyl-carbamoyl}-phenyl)-amide::CHEMBL77105
SMILES: CN(C(=O)c1ccc(NC(=O)c2ccoc2C)cc1)c1ccc(C)cc1OCCCCCC(=O)N1CCC(CC1)N1CCCCC1
InChI Key: InChIKey=FWAIISKMGSSFIF-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V1a receptor (RAT) | BDBM50108494 (2-Methyl-furan-3-carboxylic acid (4-{[2-(6-[1,4']b...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description Evaluated for the binding affinity towards vasopressin (V1A) receptor in rat liver membrane using [3H]AVP as radioligand | Bioorg Med Chem Lett 12: 229-32 (2001) BindingDB Entry DOI: 10.7270/Q2R78FQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Rattus norvegicus (Rat)) | BDBM50108494 (2-Methyl-furan-3-carboxylic acid (4-{[2-(6-[1,4']b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description Evaluated for the binding affinity towards vasopressin (V2) receptor in rat kidney membrane using [3H]AVP as radioligand | Bioorg Med Chem Lett 12: 229-32 (2001) BindingDB Entry DOI: 10.7270/Q2R78FQP | |||||||||||
More data for this Ligand-Target Pair |