BDBM50108500 2-Methyl-furan-3-carboxylic acid [4-(methyl-{4-methyl-2-[6-(4-methyl-piperazin-1-yl)-6-oxo-hexyloxy]-phenyl}-carbamoyl)-phenyl]-amide::CHEMBL74593
SMILES: CN(C(=O)c1ccc(NC(=O)c2ccoc2C)cc1)c1ccc(C)cc1OCCCCCC(=O)N1CCN(C)CC1
InChI Key: InChIKey=HLSBJGNMECMRGP-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AVPR1A (RAT) | BDBM50108500 (2-Methyl-furan-3-carboxylic acid [4-(methyl-{4-met...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description Evaluated for the binding affinity towards vasopressin (V1A) receptor in rat liver membrane using [3H]AVP as radioligand | Bioorg Med Chem Lett 12: 229-32 (2001) BindingDB Entry DOI: 10.7270/Q2R78FQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 Receptor (Rattus norvegicus (Rat)) | BDBM50108500 (2-Methyl-furan-3-carboxylic acid [4-(methyl-{4-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description Evaluated for the binding affinity towards vasopressin (V2) receptor in rat kidney membrane using [3H]AVP as radioligand | Bioorg Med Chem Lett 12: 229-32 (2001) BindingDB Entry DOI: 10.7270/Q2R78FQP | |||||||||||
More data for this Ligand-Target Pair |