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BDBM50108642 CHEMBL27725

SMILES: CCCCc1nc(Cl)c(CC(=O)OC)n1Cc1ccc(NC(=O)c2cccc(c2C(O)=O)[N+]([O-])=O)cc1

InChI Key: InChIKey=VTPGJVFIRNPJAL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108642   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin II receptor


(RAT)		BDBM50108642
PNG
(CHEMBL27725)
Show SMILES CCCCc1nc(Cl)c(CC(=O)OC)n1Cc1ccc(NC(=O)c2cccc(c2C(O)=O)[N+]([O-])=O)cc1
Show InChI InChI=1S/C25H25ClN4O7/c1-3-4-8-20-28-23(26)19(13-21(31)37-2)29(20)14-15-9-11-16(12-10-15)27-24(32)17-6-5-7-18(30(35)36)22(17)25(33)34/h5-7,9-12H,3-4,8,13-14H2,1-2H3,(H,27,32)(H,33,34)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 400n/an/an/an/an/an/a



E. I. du Pont de Nemours& Company, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration that gave 50 percent displacement of specific binding of [3H]AII (2 nM) to Angiotensin II receptor

J Med Chem 33: 1312-29 (1990)


BindingDB Entry DOI: 10.7270/Q2TM7DCT
More data for this
Ligand-Target Pair