BDBM50109174 2,6-Dimethyl-4-{3-[3-(3-piperazin-1-yl-propyl)-ureido]-phenyl}-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester::CHEMBL124936

SMILES: COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(NC(=O)NCCCN2CCNCC2)c1

InChI Key: InChIKey=ZMBFMOCRAMFOSQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50109174 (2,6-Dimethyl-4-{3-[3-(3-piperazin-1-yl-propyl)-ure...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(NC(=O)NCCCN2CCNCC2)c1 |c:13,t:10| Show InChI InChI=1S/C25H35N5O5/c1-16-20(23(31)34-3)22(21(17(2)28-16)24(32)35-4)18-7-5-8-19(15-18)29-25(33)27-9-6-12-30-13-10-26-11-14-30/h5,7-8,15,20,22,26H,6,9-14H2,1-4H3,(H2,27,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membrane				Bioorg Med Chem Lett 12: 379-82 (2002) BindingDB Entry DOI: 10.7270/Q2DJ5DZ8
					More data for this Ligand-Target Pair