BDBM50109281 4-(2,4-Dichloro-phenylamino)-7,8-dimethoxy-benzo[g]quinoline-3-carbonitrile::CHEMBL135282

SMILES: COc1cc2cc3ncc(C#N)c(Nc4ccc(Cl)cc4Cl)c3cc2cc1OC

InChI Key: InChIKey=ARYSVFZAJYNRRS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50109281 (4-(2,4-Dichloro-phenylamino)-7,8-dimethoxy-benzo[g...) Show SMILES COc1cc2cc3ncc(C#N)c(Nc4ccc(Cl)cc4Cl)c3cc2cc1OC Show InChI InChI=1S/C22H15Cl2N3O2/c1-28-20-7-12-5-16-19(6-13(12)8-21(20)29-2)26-11-14(10-25)22(16)27-18-4-3-15(23)9-17(18)24/h3-9,11H,1-2H3,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of Src protein tryrosine kinase				Bioorg Med Chem Lett 12: 423-5 (2002) BindingDB Entry DOI: 10.7270/Q2WM1CQ7
					More data for this Ligand-Target Pair