null

SMILES: Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccno2)c1C

InChI Key: InChIKey=YBRONYXWWAUIFR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50109674 (4'-Isoxazol-5-yl-biphenyl-2-sulfonic acid (3,4-dim...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccno2)c1C Show InChI InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-20(13)23-28(24,25)19-6-4-3-5-17(19)15-7-9-16(10-8-15)18-11-12-21-26-18/h3-12,23H,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to CHO cells stably expressing human Endothelin A receptor.				Bioorg Med Chem Lett 12: 517-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0STQ
					More data for this Ligand-Target Pair
Endothelin receptor type B (Homo sapiens (Human))	BDBM50109674 (4'-Isoxazol-5-yl-biphenyl-2-sulfonic acid (3,4-dim...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccno2)c1C Show InChI InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-20(13)23-28(24,25)19-6-4-3-5-17(19)15-7-9-16(10-8-15)18-11-12-21-26-18/h3-12,23H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to CHO cells stably expressing human Endothelin B receptor.				Bioorg Med Chem Lett 12: 517-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0STQ
					More data for this Ligand-Target Pair