BDBM50109752 CHEMBL3604164

SMILES: FC(F)c1[nH]nc(C(=O)Nc2ccc(F)cc2Cl)c1Cl

InChI Key: InChIKey=MFTGLHQXJAJYOV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50109752 (CHEMBL3604164) Show SMILES FC(F)c1[nH]nc(C(=O)Nc2ccc(F)cc2Cl)c1Cl Show InChI InChI=1S/C11H6Cl2F3N3O/c12-5-3-4(14)1-2-6(5)17-11(20)9-7(13)8(10(15)16)18-19-9/h1-3,10H,(H,17,20)(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...				Bioorg Med Chem Lett 25: 3024-9 (2015) BindingDB Entry DOI: 10.7270/Q2R21350
					More data for this Ligand-Target Pair