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SMILES: COc1ccc(cc1OC1CCOC1)C(C)Cn1cc[nH]c1=O

InChI Key: InChIKey=GVGMIPXDLMJJBC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110029   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50110029
PNG
(1-{2-[4-Methoxy-3-(tetrahydro-furan-3-yloxy)-pheny...)
Show SMILES COc1ccc(cc1OC1CCOC1)C(C)Cn1cc[nH]c1=O
Show InChI InChI=1S/C17H22N2O4/c1-12(10-19-7-6-18-17(19)20)13-3-4-15(21-2)16(9-13)23-14-5-8-22-11-14/h3-4,6-7,9,12,14H,5,8,10-11H2,1-2H3,(H,18,20)
PDB

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 241n/an/an/an/an/an/a



Janssen-Cilag

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes

Bioorg Med Chem Lett 12: 653-8 (2002)


BindingDB Entry DOI: 10.7270/Q2DV1KF6
More data for this
Ligand-Target Pair