BDBM50110033 1-{2-[3-(2-Indan-2-yl-ethoxy)-4-methoxy-phenyl]-propyl}-1,3-dihydro-imidazol-2-ylidene-cyanamide::CHEMBL158616
SMILES: COc1ccc(cc1OCCC1Cc2ccccc2C1)C(C)Cn1ccnc1NC#N
InChI Key: InChIKey=KEZXMUYHYHUAFY-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50110033 (1-{2-[3-(2-Indan-2-yl-ethoxy)-4-methoxy-phenyl]-pr...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag Curated by ChEMBL | Assay Description Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes | Bioorg Med Chem Lett 12: 653-8 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KF6 | |||||||||||
More data for this Ligand-Target Pair |