BDBM50110034 1-{2-[4-Difluoromethoxy-3-(5-phenyl-pentyloxy)-phenyl]-propyl}-1,3-dihydro-imidazol-2-ylidene-cyanamide::CHEMBL160463

SMILES: CC(Cn1ccnc1NC#N)c1ccc(OC(F)F)c(OCCCCCc2ccccc2)c1

InChI Key: InChIKey=YIZJKOHNEXJBBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50110034 (1-{2-[4-Difluoromethoxy-3-(5-phenyl-pentyloxy)-phe...) Show SMILES CC(Cn1ccnc1NC#N)c1ccc(OC(F)F)c(OCCCCCc2ccccc2)c1 Show InChI InChI=1S/C25H28F2N4O2/c1-19(17-31-14-13-29-25(31)30-18-28)21-11-12-22(33-24(26)27)23(16-21)32-15-7-3-6-10-20-8-4-2-5-9-20/h2,4-5,8-9,11-14,16,19,24H,3,6-7,10,15,17H2,1H3,(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes				Bioorg Med Chem Lett 12: 653-8 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KF6
					More data for this Ligand-Target Pair