BDBM50110041 1-[1-(3-Cyclopentyloxy-4-methoxy-phenyl)-cyclopropylmethyl]-1,3-dihydro-imidazol-2-one::CHEMBL158431

SMILES: COc1ccc(cc1OC1CCCC1)C1(Cn2cc[nH]c2=O)CC1

InChI Key: InChIKey=QRXNFMNALVKMSM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50110041 (1-[1-(3-Cyclopentyloxy-4-methoxy-phenyl)-cycloprop...) Show SMILES COc1ccc(cc1OC1CCCC1)C1(Cn2cc[nH]c2=O)CC1 Show InChI InChI=1S/C19H24N2O3/c1-23-16-7-6-14(12-17(16)24-15-4-2-3-5-15)19(8-9-19)13-21-11-10-20-18(21)22/h6-7,10-12,15H,2-5,8-9,13H2,1H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	341	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes				Bioorg Med Chem Lett 12: 653-8 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KF6
					More data for this Ligand-Target Pair