BDBM50110045 1-{2-[4-Methoxy-3-(tetrahydro-furan-3-yloxy)-phenyl]-propyl}-1,3-dihydro-imidazol-2-ylidene-cyanamide::CHEMBL160144

SMILES: COc1ccc(cc1OC1CCOC1)C(C)Cn1ccnc1NC#N

InChI Key: InChIKey=FPANWOUZARXEKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50110045 (1-{2-[4-Methoxy-3-(tetrahydro-furan-3-yloxy)-pheny...) Show SMILES COc1ccc(cc1OC1CCOC1)C(C)Cn1ccnc1NC#N Show InChI InChI=1S/C18H22N4O3/c1-13(10-22-7-6-20-18(22)21-12-19)14-3-4-16(23-2)17(9-14)25-15-5-8-24-11-15/h3-4,6-7,9,13,15H,5,8,10-11H2,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes				Bioorg Med Chem Lett 12: 653-8 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KF6
					More data for this Ligand-Target Pair