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BDBM50110046 1-[2-(3-Cyclopropylmethoxy-4-difluoromethoxy-phenyl)-propyl]-1,3-dihydro-imidazol-2-ylidene-cyanamide::CHEMBL158977

SMILES: CC(Cn1ccnc1NC#N)c1ccc(OC(F)F)c(OCC2CC2)c1

InChI Key: InChIKey=PLELSWHATSZTIO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110046   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50110046
PNG
(1-[2-(3-Cyclopropylmethoxy-4-difluoromethoxy-pheny...)
Show SMILES CC(Cn1ccnc1NC#N)c1ccc(OC(F)F)c(OCC2CC2)c1
Show InChI InChI=1S/C18H20F2N4O2/c1-12(9-24-7-6-22-18(24)23-11-21)14-4-5-15(26-17(19)20)16(8-14)25-10-13-2-3-13/h4-8,12-13,17H,2-3,9-10H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 22n/an/an/an/an/an/a



Janssen-Cilag

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes

Bioorg Med Chem Lett 12: 653-8 (2002)


BindingDB Entry DOI: 10.7270/Q2DV1KF6
More data for this
Ligand-Target Pair