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SMILES: COc1ccc(cc1OC1CCOC1)C(C)(F)Cn1cc[nH]c1=O

InChI Key: InChIKey=IDRCNGCIZNSRDJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110048   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50110048
PNG
(1-{2-Fluoro-2-[4-methoxy-3-(tetrahydro-furan-3-ylo...)
Show SMILES COc1ccc(cc1OC1CCOC1)C(C)(F)Cn1cc[nH]c1=O
Show InChI InChI=1S/C17H21FN2O4/c1-17(18,11-20-7-6-19-16(20)21)12-3-4-14(22-2)15(9-12)24-13-5-8-23-10-13/h3-4,6-7,9,13H,5,8,10-11H2,1-2H3,(H,19,21)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 327n/an/an/an/an/an/a



Janssen-Cilag

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes

Bioorg Med Chem Lett 12: 653-8 (2002)


BindingDB Entry DOI: 10.7270/Q2DV1KF6
More data for this
Ligand-Target Pair