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SMILES: CC(Cn1cc[nH]c1=O)c1ccc(OC(F)(F)F)c(OC2CCCC2)c1

InChI Key: InChIKey=QVWKYJCPMLPKOA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110049   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50110049
PNG
(1-[2-(3-Cyclopentyloxy-4-trifluoromethoxy-phenyl)-...)
Show SMILES CC(Cn1cc[nH]c1=O)c1ccc(OC(F)(F)F)c(OC2CCCC2)c1
Show InChI InChI=1S/C18H21F3N2O3/c1-12(11-23-9-8-22-17(23)24)13-6-7-15(26-18(19,20)21)16(10-13)25-14-4-2-3-5-14/h6-10,12,14H,2-5,11H2,1H3,(H,22,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Janssen-Cilag

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes

Bioorg Med Chem Lett 12: 653-8 (2002)


BindingDB Entry DOI: 10.7270/Q2DV1KF6
More data for this
Ligand-Target Pair