BDBM50110186 CHEMBL3604468

SMILES: C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(N)=O)ncc1Br

InChI Key: InChIKey=SPRSVKHLNRKLHA-BIJWWHILSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50110186 (CHEMBL3604468) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(N)=O)ncc1Br |r| Show InChI InChI=1S/C14H17BrN4O3S/c1-8(20)9(2)22-13-12(15)7-17-14(19-13)18-10-3-5-11(6-4-10)23(16)21/h3-9,20H,16H2,1-2H3,(H,17,18,19)/t8-,9-,23?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin)				Bioorg Med Chem Lett 25: 3420-35 (2015) BindingDB Entry DOI: 10.7270/Q2736SQ1
					More data for this Ligand-Target Pair