BDBM50110211 8,9-Dichloro-5-oxo-1,5,6,10b-tetrahydro-pyrazolo[1,5-c]quinazoline-2-carboxylic acid::CHEMBL8693

SMILES: OC(=O)C1=NN2C(C1)c1cc(Cl)c(Cl)cc1NC2=O

InChI Key: InChIKey=ZWJLRGZWJBGXGV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110211 (8,9-Dichloro-5-oxo-1,5,6,10b-tetrahydro-pyrazolo[1...) Show SMILES OC(=O)C1=NN2C(C1)c1cc(Cl)c(Cl)cc1NC2=O |t:3| Show InChI InChI=1S/C11H7Cl2N3O3/c12-5-1-4-7(2-6(5)13)14-11(19)16-9(4)3-8(15-16)10(17)18/h1-2,9H,3H2,(H,14,19)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Moscow State University Curated by ChEMBL					Assay Description Binding selectivity towards N-methyl-D-aspartate glutamate receptor 1 was determined by using [3H]- glycine/NMDA				J Med Chem 46: 4063-9 (2003) Article DOI: 10.1021/jm030833a BindingDB Entry DOI: 10.7270/Q2445KVC
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50110211 (8,9-Dichloro-5-oxo-1,5,6,10b-tetrahydro-pyrazolo[1...) Show SMILES OC(=O)C1=NN2C(C1)c1cc(Cl)c(Cl)cc1NC2=O |t:3| Show InChI InChI=1S/C11H7Cl2N3O3/c12-5-1-4-7(2-6(5)13)14-11(19)16-9(4)3-8(15-16)10(17)18/h1-2,9H,3H2,(H,14,19)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Inhibition by displacing [3H]-Glycine of N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes				J Med Chem 45: 1035-44 (2002) BindingDB Entry DOI: 10.7270/Q2WD3ZW6
					More data for this Ligand-Target Pair