BDBM50110287 (3-Piperidin-1-yl-propyl)-quinolin-4-yl-amine; Oxalic acid::CHEMBL14753

SMILES: C(CNc1ccnc2ccccc12)CN1CCCCC1

InChI Key: InChIKey=BVSJYYGMUXJMTE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50110287 ((3-Piperidin-1-yl-propyl)-quinolin-4-yl-amine; Oxa...) Show SMILES C(CNc1ccnc2ccccc12)CN1CCCCC1 Show InChI InChI=1S/C17H23N3/c1-4-12-20(13-5-1)14-6-10-18-17-9-11-19-16-8-3-2-7-15(16)17/h2-3,7-9,11H,1,4-6,10,12-14H2,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Affinity for displacement of [125I]-iodoproxyfan from human histamine H3 receptors stably expressed in CHO cells				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair
Histamine N-methyltransferase (Rattus norvegicus)	BDBM50110287 ((3-Piperidin-1-yl-propyl)-quinolin-4-yl-amine; Oxa...) Show SMILES C(CNc1ccnc2ccccc12)CN1CCCCC1 Show InChI InChI=1S/C17H23N3/c1-4-12-20(13-5-1)14-6-10-18-17-9-11-19-16-8-3-2-7-15(16)17/h2-3,7-9,11H,1,4-6,10,12-14H2,(H,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair