BDBM50110293 CHEMBL14860::Methyl-(2-piperidin-1-yl-ethyl)-quinolin-4-yl-amine; Oxalic acid

SMILES: CN(CCN1CCCCC1)c1ccnc2ccccc12

InChI Key: InChIKey=ZPRYWHQVVOHBQV-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50110293 (CHEMBL14860 | Methyl-(2-piperidin-1-yl-ethyl)-quin...) Show SMILES CN(CCN1CCCCC1)c1ccnc2ccccc12 Show InChI InChI=1S/C17H23N3/c1-19(13-14-20-11-5-2-6-12-20)17-9-10-18-16-8-4-3-7-15(16)17/h3-4,7-10H,2,5-6,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	362	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Affinity for displacement of [125I]-iodoproxyfan from human histamine H3 receptors stably expressed in CHO cells				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair
Histamine N-methyltransferase (Rattus norvegicus)	BDBM50110293 (CHEMBL14860 | Methyl-(2-piperidin-1-yl-ethyl)-quin...) Show SMILES CN(CCN1CCCCC1)c1ccnc2ccccc12 Show InChI InChI=1S/C17H23N3/c1-19(13-14-20-11-5-2-6-12-20)17-9-10-18-16-8-4-3-7-15(16)17/h3-4,7-10H,2,5-6,11-14H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair