BDBM50110515 3-Fluoro-5-(2-isopropyl-4,4-dimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile::CHEMBL163833

SMILES: CC(C)C1Nc2ccc(cc2C(C)(C)O1)-c1cc(F)cc(c1)C#N

InChI Key: InChIKey=JSNIBELMASXADL-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50110515 (3-Fluoro-5-(2-isopropyl-4,4-dimethyl-1,4-dihydro-2...) Show SMILES CC(C)C1Nc2ccc(cc2C(C)(C)O1)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C20H21FN2O/c1-12(2)19-23-18-6-5-14(10-17(18)20(3,4)24-19)15-7-13(11-22)8-16(21)9-15/h5-10,12,19,23H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell line				Bioorg Med Chem Lett 12: 787-90 (2002) BindingDB Entry DOI: 10.7270/Q2WS8TSW
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50110515 (3-Fluoro-5-(2-isopropyl-4,4-dimethyl-1,4-dihydro-2...) Show SMILES CC(C)C1Nc2ccc(cc2C(C)(C)O1)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C20H21FN2O/c1-12(2)19-23-18-6-5-14(10-17(18)20(3,4)24-19)15-7-13(11-22)8-16(21)9-15/h5-10,12,19,23H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell line				Bioorg Med Chem Lett 12: 787-90 (2002) BindingDB Entry DOI: 10.7270/Q2WS8TSW
					More data for this Ligand-Target Pair