BDBM50110521 6-(5-Cyano-thiophen-3-yl)-4,4-dimethyl-2-trifluoromethyl-4H-benzo[d][1,3]oxazine-1-carboxylic acid methyl ester::CHEMBL164331

SMILES: COC(=O)N1C(OC(C)(C)c2cc(ccc12)-c1csc(c1)C#N)C(F)(F)F

InChI Key: InChIKey=XBKAZNZQGBKVLS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50110521 (6-(5-Cyano-thiophen-3-yl)-4,4-dimethyl-2-trifluoro...) Show SMILES COC(=O)N1C(OC(C)(C)c2cc(ccc12)-c1csc(c1)C#N)C(F)(F)F Show InChI InChI=1S/C18H15F3N2O3S/c1-17(2)13-7-10(11-6-12(8-22)27-9-11)4-5-14(13)23(16(24)25-3)15(26-17)18(19,20)21/h4-7,9,15H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell line				Bioorg Med Chem Lett 12: 787-90 (2002) BindingDB Entry DOI: 10.7270/Q2WS8TSW
					More data for this Ligand-Target Pair