BDBM50110650 3,5-Dichloro-N-{3-(3,4-dichloro-phenyl)-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-2-[(Z)-2-piperazin-1-yl-ethoxyimino]-pentyl}-N-methyl-benzamide::CHEMBL167546

SMILES: CN(C\C(=N/OCCN1CCNCC1)C(CCN1CCC(CC1)N1CCCCC1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=GTFKLIDYRPSITH-ZSJGZSGZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 1 receptor (Homo sapiens (Human))	BDBM50110650 (3,5-Dichloro-N-{3-(3,4-dichloro-phenyl)-5-(2-oxo-[...) Show SMILES CN(C\C(=N/OCCN1CCNCC1)C(CCN1CCC(CC1)N1CCCCC1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C35H46Cl4N6O3/c1-42(35(47)26-20-27(36)23-28(37)21-26)24-33(41-48-19-18-44-16-10-40-11-17-44)30(25-5-6-31(38)32(39)22-25)9-15-43-13-7-29(8-14-43)45-12-3-2-4-34(45)46/h5-6,20-23,29-30,40H,2-4,7-19,24H2,1H3/b41-33+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against recombinant human tachykinin receptor 1 in CHO cells using [3H]-Sar SP as a radioligand				Bioorg Med Chem Lett 12: 833-6 (2002) BindingDB Entry DOI: 10.7270/Q2BG2N96
					More data for this Ligand-Target Pair
Neurokinin 2 receptor (Homo sapiens (Human))	BDBM50110650 (3,5-Dichloro-N-{3-(3,4-dichloro-phenyl)-5-(2-oxo-[...) Show SMILES CN(C\C(=N/OCCN1CCNCC1)C(CCN1CCC(CC1)N1CCCCC1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C35H46Cl4N6O3/c1-42(35(47)26-20-27(36)23-28(37)21-26)24-33(41-48-19-18-44-16-10-40-11-17-44)30(25-5-6-31(38)32(39)22-25)9-15-43-13-7-29(8-14-43)45-12-3-2-4-34(45)46/h5-6,20-23,29-30,40H,2-4,7-19,24H2,1H3/b41-33+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against recombinant human tachykinin receptor 2 in CHO cells using [3H]-NKA as a radioligand				Bioorg Med Chem Lett 12: 833-6 (2002) BindingDB Entry DOI: 10.7270/Q2BG2N96
					More data for this Ligand-Target Pair