BDBM50110680 CHEMBL3605828

SMILES: CCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1

InChI Key: InChIKey=LUJKHRHCGQVVAQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM50110680 (CHEMBL3605828) Show SMILES CCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1 Show InChI InChI=1S/C27H30FN3O4S/c1-5-35-22-11-13-25(24(28)15-22)30-36(33,34)23-12-6-18-16-31(17-19(18)14-23)26(32)29-21-9-7-20(8-10-21)27(2,3)4/h6-15,30H,5,16-17H2,1-4H3,(H,29,32)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...				Bioorg Med Chem 23: 5922-31 (2015) BindingDB Entry DOI: 10.7270/Q2639RJ6
					More data for this Ligand-Target Pair