BDBM50110688 CHEMBL3605824

SMILES: CCOc1cc(F)ccc1NS(=O)(=O)c1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=HHJXTKVAIKQFLW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM50110688 (CHEMBL3605824) Show SMILES CCOc1cc(F)ccc1NS(=O)(=O)c1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C27H30FN3O4S/c1-5-35-25-15-21(28)9-13-24(25)30-36(33,34)23-12-6-18-16-31(17-19(18)14-23)26(32)29-22-10-7-20(8-11-22)27(2,3)4/h6-15,30H,5,16-17H2,1-4H3,(H,29,32)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	733	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...				Bioorg Med Chem 23: 5922-31 (2015) BindingDB Entry DOI: 10.7270/Q2639RJ6
					More data for this Ligand-Target Pair