BDBM50110715 5-Methoxymethyl-3-[4-(4,4,4-trifluoro-3-hydroxy-butoxy)-phenyl]-oxazolidin-2-one::CHEMBL18101
SMILES: COC[C@@H]1CN(C(=O)O1)c1ccc(OCC[C@H](O)C(F)(F)F)cc1
InChI Key: InChIKey=IALVDLPLCLFBCF-STQMWFEESA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoamine oxidase (Bos taurus) | BDBM50110715 (5-Methoxymethyl-3-[4-(4,4,4-trifluoro-3-hydroxy-bu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibition of bovine brain mitochondrial Monoamine oxidase A (MAO-A) compared to toloxatone | J Med Chem 45: 1180-3 (2002) BindingDB Entry DOI: 10.7270/Q28W3F11 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine oxidase (Bos taurus) | BDBM50110715 (5-Methoxymethyl-3-[4-(4,4,4-trifluoro-3-hydroxy-bu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibition of bovine brain mitochondrial Monoamine oxidase B (MAO-B) compared to toloxatone | J Med Chem 45: 1180-3 (2002) BindingDB Entry DOI: 10.7270/Q28W3F11 | |||||||||||
More data for this Ligand-Target Pair |