BDBM50111183 (2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-(naphthalen-1-yl)-2-[(naphthalen-2-ylmethyl)amino]pentanamide::MK-54::N-Alkylaminoacid derivative
SMILES: [NH3+]C(=N)NCCC[C@H](NCc1ccc2ccccc2c1)C(=O)Nc1cccc2ccccc12
InChI Key: InChIKey=MOENHRSRNGVQFI-VWLOTQADSA-O
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM50111183 ((2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 1 receptor | Bioorg Med Chem Lett 12: 1039-42 (2002) BindingDB Entry DOI: 10.7270/Q2833SKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 3 (Homo sapiens (Human)) | BDBM50111183 ((2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 3 receptor | Bioorg Med Chem Lett 12: 1039-42 (2002) BindingDB Entry DOI: 10.7270/Q2833SKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50111183 ((2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 4 receptor | Bioorg Med Chem Lett 12: 1039-42 (2002) BindingDB Entry DOI: 10.7270/Q2833SKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human)) | BDBM50111183 ((2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 5 receptor | Bioorg Med Chem Lett 12: 1039-42 (2002) BindingDB Entry DOI: 10.7270/Q2833SKD | |||||||||||
More data for this Ligand-Target Pair |