BDBM50111482 CHEMBL3604917

SMILES: C=CC(=O)Nc1cc(Nc2cc[nH]n2)nc(n1)-c1ccccc1

InChI Key: InChIKey=YLMKDUHUYYITGE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50111482 (CHEMBL3604917) Show SMILES C=CC(=O)Nc1cc(Nc2cc[nH]n2)nc(n1)-c1ccccc1 Show InChI InChI=1S/C16H14N6O/c1-2-15(23)19-14-10-13(18-12-8-9-17-22-12)20-16(21-14)11-6-4-3-5-7-11/h2-10H,1H2,(H3,17,18,19,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TU Dortmund University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) expressed in Sf9 cells pre-incubated for 30 mins before substrate and ATP addition by homogeneous time-...				J Med Chem 58: 6844-63 (2015) BindingDB Entry DOI: 10.7270/Q2WM1G59
					More data for this Ligand-Target Pair